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Drug ReportsErythromycin lactobionate
Erythromycin lactobionate
Benzamycin, E.e.s, Ery-tab, Eryc, Erygel, Eryped, Erythrerm, Erythrocin, Erythromycin, Eryzole, Ilosone, Ilotycin, Pediazole (erythromycin lactobionate) is a small molecule pharmaceutical. Erythromycin lactobionate was first approved as Ilotycin on 1982-01-01. It is used to treat acne vulgaris, bacterial eye infections, bacterial infections, campylobacter infections, and chancroid amongst others in the USA.
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
digestive system diseasesD004066
respiratory tract diseasesD012140
eye diseasesD005128
urogenital diseasesD000091642
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
Erythrocin, Erythromycin lactobionate (discontinued: Erythrocin, Erythromycin, Erythromycin lactobionate)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Erythromycin lactobionate
Tradename
Company
Number
Date
Products
ERYTHROCINHospiraN-050609 RX1986-09-24
1 products, RLD, RS
Show 2 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
erythrocin lactobionateANDA2024-02-22
erythrocin stearateANDA2015-07-31
erythromycin lactobionateANDA2024-11-20
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
— D10: Anti-acne preparations
— D10A: Anti-acne preparations for topical use
— D10AF: Antiinfectives for treatment of acne
— D10AF02: Erythromycin
— D10AF52: Erythromycin, combinations
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01F: Macrolides, lincosamides and streptogramins
— J01FA: Macrolides
— J01FA01: Erythromycin
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AA: Antibiotics, ophthalmologic
— S01AA17: Erythromycin
HCPCS
Code
Description
J1364
Injection, erythromycin lactobionate, per 500 mg
Clinical
Clinical Trials
195 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———9213115
Premature birthD047928EFO_0003917O60——21811
Premature rupture fetal membranesD005322—O42——41510
RuptureD012421————41510
InfectionsD007239EFO_0000544——1—168
Communicable diseasesD003141———1—157
Colorectal neoplasmsD015179———1—214
ObesityD009765EFO_0001073E66.9———134
Wounds and injuriesD014947—T14.8———134
EmergenciesD004630—————123
Show 28 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PneumoniaD011014EFO_0003106J18—13—58
Respiratory insufficiencyD012131—J96.9—22—58
HemorrhageD006470MP_0001914R58—13—15
Gastrointestinal hemorrhageD006471—K92.2—13—15
LymphomaD008223—C85.9131——4
Lung neoplasmsD008175—C34.90——1—23
HypoventilationD007040————1—23
Chlamydia infectionsD002690EFO_0007205A74.9—11——2
Non-small-cell lung carcinomaD002289————1—12
Hodgkin diseaseD006689—C81—11——2
Show 16 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SyndromeD013577——22——35
LeukemiaD007938—C9522———4
FibrosisD005355——11——34
HypercapniaD006935———1——34
GastroparesisD018589EFO_1000948K31.84—3———3
Breast neoplasmsD001943EFO_0003869C50—2——13
B-cell chronic lymphocytic leukemiaD015451—C91.112———3
Myeloid leukemia acuteD015470—C92.011———2
Myeloid leukemiaD007951—C9211———2
Non-hodgkin lymphomaD008228—C85.912———2
Show 39 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SclerosisD012598——1———23
Diabetes mellitusD003920EFO_0000400E08-E131———12
Amyotrophic lateral sclerosisD000690EFO_0000253G12.212————2
Motor neuron diseaseD016472EFO_0003782G12.22————2
OsteomyelitisD010019EFO_0003102M861————1
Chronic renal insufficiencyD051436—N181————1
Kidney diseasesD007674EFO_0003086N081————1
Precancerous conditionsD011230——1————1
Oral leukoplakiaD007972HP_0002745K13.211————1
LeukoplakiaD007971——1————1
Show 11 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DepressionD003863—F33.9————44
Obstructive sleep apneaD020181EFO_0003918G47.33————44
ApneaD001049—R06.81————33
Sleep apnea syndromesD012891EFO_0003877G47.3————33
Heart failureD006333EFO_0003144I50————22
BronchiectasisD001987—J47————22
PregnancyD011247EFO_0002950Z33.1————22
DermatitisD003872—L30.9————22
Postoperative nausea and vomitingD020250EFO_0004888—————22
Autistic disorderD001321EFO_0003758F84.0————22
Show 119 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameErythromycin lactobionate
INNerythromycin
Description
Erythromycin A is an erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. It is an erythromycin and a cyclic ketone. It is functionally related to an erythronolide A. It is a conjugate base of an erythromycin A(1+).
Classification
Small molecule
Drug classantibiotics (Streptomyces strain)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O.O=C(O)[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)CO
Identifiers
PDB—
CAS-ID114-07-8
RxCUI4053
ChEMBL IDCHEMBL1200506
ChEBI ID—
PubChem CID12560
DrugBankDB00199
UNII ID63937KV33D (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
Pfizer – Protalix BioTherapeutics
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Estimated US medical usage
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 608 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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11,367 adverse events reported
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